Tadalafil

1 paper4 findings

PubChem 110635 ChEBI 71940

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: Taichung Veterans General Hospital

Humans1

Outcomes

Primary angle-closure glaucoma

no changein humans1

1 study

Tadalafil has no effect on primary angle-closure glaucoma in humans.
Humanslower urinary tract symptomsup to 5 yearsmales
Risk of glaucoma among patients using tadalafil for lower urinary tract symptoms: a multinational cohort study
The British journal of ophthalmology4 Aug 2026

Associations

Primary open-angle glaucoma

upin humans1HR 1.33

1 study

Tadalafil raises the risk of primary open-angle glaucoma in humans (HR 1.33, 95% CI 1.05–1.67).
Humanslower urinary tract symptomsup to 5 yearsmales
Risk of glaucoma among patients using tadalafil for lower urinary tract symptoms: a multinational cohort study
The British journal of ophthalmology4 Aug 2026

Latest

1 in 12 months

The British Journal of Ophthalmology9 Aug

Risk of glaucoma among patients using tadalafil for lower urinary tract symptoms: a multinational cohort study

Cohort study in peopleGlaucoma

Paper

Tadalafil

Outcomes

Associations

Latest

Risk of glaucoma among patients using tadalafil for lower urinary tract symptoms: a multinational cohort study

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