RFOXN1 fusion protein

RFOXN1 fusion protein has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Feb 8, 2023: “Recombinant FOXN1 fusion protein increases T cell generation in aged mice”.

Intervention

1 paper studies it2 findingsUpdated

See all 1

None of its findings points the other way.

  • 1 lab
  • Funder: National Institute on Aging
  • Animals1

What did studies of RFOXN1 fusion protein find?

2

Studies of RFOXN1 fusion protein measured 2 outcomes; the most studied are peripheral T cells (1 study) and T cell generation (1).

Peripheral T cells

upin mice1

1 study
  1. RFOXN1 fusion protein increases peripheral T cells in mice.

    “increased number of T cells in peripheral lymphoid organ”

    Animalsaged micefusion protein containing the N-terminal of CCR9, FOXN1 and a protein transduction domain

    Recombinant FOXN1 fusion protein increases T cell generation in aged mice

    Research squarePreprint

More on Peripheral T cells

T cell generation

upin mice1

1 study
  1. RFOXN1 fusion protein increases T cell generation in mice.

    “when injected intravenously into aged mice, the rFOXN1 fusion protein migrates into the thymus and enhances thymopoiesis, resulting in increased T cell generation in the thymus”

    Animalsaged micefusion protein containing the N-terminal of CCR9, FOXN1 and a protein transduction domainthymus

    Recombinant FOXN1 fusion protein increases T cell generation in aged mice

    Research squarePreprint

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