Recombinant acid sphingomyelinase
Intervention1 paper1 finding
- Cells1
Outcomes
1PAX7+ MuSCs
downin human cells1
1 study
PAX7+ MuSCs
downin human cells1
Recombinant acid sphingomyelinase decreases PAX7+ MuSCs in human cells.
Cellsin young culturesrecombinantprimary muscle cells
Aged human muscle secretes an enzyme that impairs stem cell maintenance · bioRxiv · 2 Oct 2026 · Preprint
Latest
1CellsPreprint
Aged human muscle secretes an enzyme that impairs stem cell maintenance
Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.