Proximal femoral nail

Proximal femoral nail has been studied in 5 papers since 2021: 4 observational studies in people, 1 review. The newest paper, Oct 17, 2025: “Comparative Effectiveness of the Proximal Femoral Nail and Dynamic Hip Screw Fixation in Intertrochanteric Femur Fractures: A Systematic Review and Meta-Analysis”.

Exposure

5 papers study it4 findingsUpdated

See all 5

None of its findings points the other way.

  • 1 lab in 1 country
  • Humans4

What did studies of Proximal femoral nail find?

4

Studies of Proximal femoral nail measured 4 outcomes; the most studied are mortality (1 study), total complications (1) and intraoperative blood loss (1).

Mortality

no changein humans1

1 study
  1. Proximal femoral nail has no effect on mortality in humans.

    “no significant differences were observed between groups regarding implant failure rates, mortality, or long-term functional outcomes, as measured by the Harris Hip Score”

    Reviewin patients with intertrochanteric femur fractures

    Comparative Effectiveness of the Proximal Femoral Nail and Dynamic Hip Screw Fixation in Intertrochanteric Femur Fractures: A Systematic Review and Meta-Analysis

    Cureus

Total complications

downin humans1RR 0.46

1 study
  1. Proximal femoral nail decreases total complications in humans (RR 0.46, 95% CI 0.31-0.68).

    “PFN was associated with significantly lower total complication rates (risk ratio (RR): 0.46, 95% CI: 0.31-0.68) and reduced infection risk”

    Reviewin patients with intertrochanteric femur fractures

    Comparative Effectiveness of the Proximal Femoral Nail and Dynamic Hip Screw Fixation in Intertrochanteric Femur Fractures: A Systematic Review and Meta-Analysis

    Cureus

Intraoperative blood loss

downin humans1

1 study
  1. Proximal femoral nail decreases intraoperative blood loss in humans (MD -115.01 mL, 95% CI -132.05 to -97.98).

    “intraoperative blood loss was substantially lower (MD: -115.01 mL, 95% CI: -132.05 to -97.98)”

    Reviewin patients with intertrochanteric femur fractures

    Comparative Effectiveness of the Proximal Femoral Nail and Dynamic Hip Screw Fixation in Intertrochanteric Femur Fractures: A Systematic Review and Meta-Analysis

    Cureus

Operative time

downin humans1

1 study
  1. Proximal femoral nail decreases operative time in humans (MD -12.30 min, 95% CI -17.33 to -7.28).

    “Operative time was significantly shorter with PFN compared to DHS (mean difference (MD): -12.30 minutes, 95% confidence interval (CI): -17.33 to -7.28)”

    Reviewin patients with intertrochanteric femur fractures

    Comparative Effectiveness of the Proximal Femoral Nail and Dynamic Hip Screw Fixation in Intertrochanteric Femur Fractures: A Systematic Review and Meta-Analysis

    Cureus

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