Phytotherapeutic intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 2 countries

Human trial1

Outcomes

Physical function

upin humans1

1 study

Phytotherapeutic intervention improves physical function in humans (effect size 0.73).
Human trialchronic MSDs16-weekn = 180
Development and Clinical Evaluation of the Unified Musculoskeletal Dysfunction Index and Unified Musculoskeletal Aging Index in Chronic Musculoskeletal Disorders
Research Square11 Aug 2026Preprint

Model-derived musculoskeletal biological age

downin humans1

1 study

Phytotherapeutic intervention decreases model-derived musculoskeletal biological age in humans (from 68.55 to 64.10 years, -67.9% biological age acceleration gap).
Human trialchronic MSDs16-weekn = 180
Development and Clinical Evaluation of the Unified Musculoskeletal Dysfunction Index and Unified Musculoskeletal Aging Index in Chronic Musculoskeletal Disorders
Research Square11 Aug 2026Preprint

More on Model-derived musculoskeletal biological age

Unified Musculoskeletal Aging Index

downin humans1

1 study

Phytotherapeutic intervention decreases Unified Musculoskeletal Aging Index in humans (from 0.264 to 0.0846).
Human trialchronic MSDs16-weekn = 180
Development and Clinical Evaluation of the Unified Musculoskeletal Dysfunction Index and Unified Musculoskeletal Aging Index in Chronic Musculoskeletal Disorders
Research Square11 Aug 2026Preprint

More on Unified Musculoskeletal Aging Index

Unified Musculoskeletal Dysfunction Index

downin humans1

1 study

Phytotherapeutic intervention decreases Unified Musculoskeletal Dysfunction Index in humans (from 2.64 to 0.846).
Human trialchronic MSDs16-weekn = 180
Development and Clinical Evaluation of the Unified Musculoskeletal Dysfunction Index and Unified Musculoskeletal Aging Index in Chronic Musculoskeletal Disorders
Research Square11 Aug 2026Preprint

More on Unified Musculoskeletal Dysfunction Index

Latest

1 in 12 months

Research Square12 Aug

Development and Clinical Evaluation of the Unified Musculoskeletal Dysfunction Index and Unified Musculoskeletal Aging Index in Chronic Musculoskeletal Disorders

Preprint: randomised trial in 180 peopleMusculoskeletal disease

Paper

Phytotherapeutic intervention

Outcomes

Latest

Development and Clinical Evaluation of the Unified Musculoskeletal Dysfunction Index and Unified Musculoskeletal Aging Index in Chronic Musculoskeletal Disorders

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