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Ocimum tenuiflorum

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Human trial1

Outcomes

4

Acute stress response

downin humans1

1 study

  1. Ocimum tenuiflorum decreases acute stress response in humans (p = 0.001).

    “buffered stress responses after exposure to the MAST as demonstrated by significantly lower concentrations in salivary cortisol (p = 0.001)”

    Human trialadults experiencing stress undergoing MASTstandardized extract (HolixerTM)125 mg twice daily8 weeksn = 100

    A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress

    Frontiers in nutritionSep 2, 2022

Cortisol

downin humans1

1 study

  1. Ocimum tenuiflorum decreases cortisol in humans (p = 0.025).

    “at week 8, concentrations in hair cortisol were also lower (p = 0.025)”

    Human trialadults experiencing stressstandardized extract (HolixerTM)hair125 mg twice daily8 weeksn = 100

    A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress

    Frontiers in nutritionSep 2, 2022

More on Cortisol

Insomnia

downin humans1

1 study

  1. Ocimum tenuiflorum decreases insomnia in humans (p = 0.025).

    “greater improvements in PSS (p = 0.003) and AIS (p = 0.025) scores”

    Human trialadults experiencing stressstandardized extract (HolixerTM)125 mg twice daily8 weeksn = 100

    A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress

    Frontiers in nutritionSep 2, 2022

More on Insomnia

Perceived stress

downin humans1

1 study

  1. Ocimum tenuiflorum decreases perceived stress in humans (p = 0.003).

    “Ocimum tenuiflorum supplementation was associated with greater improvements in PSS (p = 0.003)”

    Human trialadults experiencing stressstandardized extract (HolixerTM)125 mg twice daily8 weeksn = 100

    A randomized, double-blind, placebo-controlled trial investigating the effects of an Ocimum tenuiflorum (Holy Basil) extract (HolixerTM) on stress, mood, and sleep in adults experiencing stress

    Frontiers in nutritionSep 2, 2022

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