Nail-plate combination

Nail-plate combination has been studied in 2 papers since 2025: 2 observational studies in people; 1 in the past year. The newest paper, May 27, 2026: “Comparative Analysis of Nail Plate Combination Over Alternative Fixation Constructs in Low-Energy Distal Femur Fractures: Recovery of Ambulatory Status and Outcomes”.

Exposure

2 papers study it4 findingsUpdated

See all 2 papers on nail-plate combination

At a glance

The findings reach people, from one lab or study. 2 independent labs in 1 country.

“NPC demonstrated lower average ambulatory impairment score over LLP: 3 weeks (-0.8; P = 0.002)”
Comparative Analysis of Nail Plate Combination Over Alternative Fixation Constructs in Low-Energy Distal Femur Fractures: Recovery of Ambulatory Status and OutcomesJournal of orthopaedic trauma2026doi:10.1097/bot.0000000000003230

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 2 independent labs in 1 country
  • Funders: National Center for Advancing Translational Sciences and 1 more
  • Humans2

What did studies of nail-plate combination find?

4

Studies of nail-plate combination measured 4 outcomes, among them radiographic union, mortality and ambulatory impairment score.

Radiographic union

no changein humans1

1 study
  1. Nail-plate combination was not clearly linked with radiographic union in humans (low-energy distal femur fracture) (P = 0.104).

    “Radiographic union was comparable (36.3% vs. 52.9% vs. 39.6% vs. 54.5%, P = 0.104).”

    Humanslow-energy distal femur fracture

    Comparative Analysis of Nail Plate Combination Over Alternative Fixation Constructs in Low-Energy Distal Femur Fractures: Recovery of Ambulatory Status and Outcomes

    Journal of orthopaedic trauma

Mortality

downin humans1

1 study
  1. Nail-plate combination is linked with lower mortality in humans (low-energy distal femur fracture) (9% vs. 19%; P = 0.04).

    “Six-month mortality was lower in NPC than rIMN (9% vs. 19%; P = 0.04).”

    Humanslow-energy distal femur fracture6 months

    Comparative Analysis of Nail Plate Combination Over Alternative Fixation Constructs in Low-Energy Distal Femur Fractures: Recovery of Ambulatory Status and Outcomes

    Journal of orthopaedic trauma

Ambulatory impairment score

downin humans1

1 study
  1. Nail-plate combination is linked with lower ambulatory impairment score in humans (low-energy distal femur fracture) (-0.8, P = 0.002).

    “NPC demonstrated lower average ambulatory impairment score over LLP: 3 weeks (-0.8; P = 0.002)”

    Humanslow-energy distal femur fracture

    Comparative Analysis of Nail Plate Combination Over Alternative Fixation Constructs in Low-Energy Distal Femur Fractures: Recovery of Ambulatory Status and Outcomes

    Journal of orthopaedic trauma

Return to baseline ambulation status

upin humans1

1 study
  1. Nail-plate combination is linked with better return to baseline ambulation status in humans (100% [11] vs 60% [71] lateral plate and 25% [3] dual plate).

    “patients treated with nail-plate had higher rates of return to baseline function (p = 0.009).”

    Humansn = 139

    Interprosthetic Femur Fractures: A Multi-Center Retrospective Study

    Journal of orthopaedic trauma

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months