MACPNS1
MACPNS1 has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest paper, May 13, 2026: “AAV tools enable functional modulation and readout of central and peripheral nervous systems in spiny mice”.
1 paper studies it2 findingsUpdated
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funder: Aligning Science Across Parkinson's
- Animals1
What did studies of MACPNS1 find?
2Studies of MACPNS1 measured 2 outcomes: colonic motility and gastric motility.
Colonic motility
upin A. dimidiatus1
1 study
Colonic motility
upin A. dimidiatus1
MACPNS1 increases colonic motility in A. dimidiatus (chemogenetic modulation).
“increasing colonic motility ex vivo”
Animalschemogenetic modulationcolon
bioRxiv (Cold Spring Harbor Laboratory)Preprint
Gastric motility
downin A. dimidiatus1
1 study
Gastric motility
downin A. dimidiatus1
MACPNS1 decreases gastric motility in A. dimidiatus (chemogenetic modulation).
“As a proof-of-concept, we used MaCPNS1 to chemogenetically modulate the activity of enteric neurons, successfully decreasing gastric motility in vivo”
Animalschemogenetic modulationstomach
bioRxiv (Cold Spring Harbor Laboratory)Preprint