Human ipsc-derived rpe cell transplantation
Human ipsc-derived rpe cell transplantation has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest paper, Oct 7, 2026: “Extensive monolayer formation after transplantation depends on an RPE subpopulation derived from human iPSCs”.
1 paper studies it2 findingsUpdated
1 new paper in 30 daysSee all 1 papers on human ipsc-derived rpe cell transplantation
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Bundesministerium für Forschung, Technologie und Raumfahrt and 1 more
- 2 of 2 findings with company ties
- Animals1
What did studies of human ipsc-derived rpe cell transplantation find?
2Studies of human ipsc-derived rpe cell transplantation measured 2 outcomes; the most studied are host outer nuclear layer (1 study) and RPE monolayer formation (1).
Host outer nuclear layer
downin mice1
1 study
Host outer nuclear layer
downin mice1
Human ipsc-derived rpe cell transplantation protects against host outer nuclear layer in mice (Sodium iodate mouse model of acute RPE depletion).
“Transplant-derived monolayers showed characteristic apicobasal polarity, RPE marker expression, phagocytosis function, and preservation of the host outer nuclear layer.”
AnimalsSodium iodate mouse model of acute RPE depletionretinal outer nuclear layer
iScience
RPE monolayer formation
upin mice1
1 study
RPE monolayer formation
upin mice1
Human ipsc-derived rpe cell transplantation increases RPE monolayer formation in mice (Sodium iodate mouse model of acute RPE depletion; compared with passage 2 cells).
“significant increase in monolayer formation capacity of passage 1 vs. 2 human induced pluripotent stem cell (iPSC)-derived RPE cells was observed three weeks post-transplantation.”
AnimalsSodium iodate mouse model of acute RPE depletion; compared with passage 2 cellsPassage 1 human iPSC-derived RPE cellsretinal pigment epitheliumThree weeks post-transplantation
iScience