Hippophae rhamnoides

1 paper5 findings

A preprint reports that Hippophae rhamnoides improves bone microarchitecture and protects against osteoporosis in ovariectomised mice, while promoting osteogenic differentiation and inhibiting osteoclast formation in mouse cells. It also reports Wnt/β-catenin activation attenuated by ERα inhibition in mouse cells. All five findings come from one lab, without human results or findings pointing the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Outcomes

Wnt/β-catenin signalling

upin mouse cells1

1 study

Hippophae rhamnoides activate wnt/β-catenin signalling in mouse cells.
Cellsattenuated by ERα inhibition
Network pharmacology and experimental evidence implicate ERα-associated β-catenin regulation in the osteoprotective effects of sea buckthorn fruit extract
Research Square16 Sep 2026Preprint

Latest

1 in 12 months

Research Square17 Sep

Network pharmacology and experimental evidence implicate ERα-associated β-catenin regulation in the osteoprotective effects of sea buckthorn fruit extract

Preprint: experiments in miceInterventions

Paper

Hippophae rhamnoides

Outcomes

Latest

Network pharmacology and experimental evidence implicate ERα-associated β-catenin regulation in the osteoprotective effects of sea buckthorn fruit extract

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