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HIL-7-FC

Intervention

1 paper studies it3 findings

Across all fields, 1 paper: none in people yet, 1 in cells

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • 3 of 3 findings with company ties
  • Cells1

Outcomes

3

Effector memory T cell

downin human cells1

1 study

  1. HIL-7-FC decreases effector memory T cell in human cells.

    “stimulation led to an increased naïve T cell as well as a decreased effector memory T cell proportions compared to controls.”

    Cellsin hip fracture patients compared to controls

    IL-7 producing immunotherapy improves ex vivo T cell functions of immunosenescent patients, especially post hip fracture

    Human vaccines & immunotherapeutics

More on Effector memory T cell

Naïve T cells

upin human cells1

1 study

  1. HIL-7-FC increases naïve T cells in human cells.

    “stimulation led to an increased naïve T cell as well as a decreased effector memory T cell proportions compared to controls.”

    Cellsin hip fracture patients compared to controls

    IL-7 producing immunotherapy improves ex vivo T cell functions of immunosenescent patients, especially post hip fracture

    Human vaccines & immunotherapeutics

More on Naïve T cells

T cell proliferation

upin human cells1

1 study

  1. HIL-7-FC increases T cell proliferation in human cells.

    “An important T cell proliferation occurred compared to controls following stimulation with hIL-7-Fc.”

    Cellsin PBMC from hip fracture patients compared to controls

    IL-7 producing immunotherapy improves ex vivo T cell functions of immunosenescent patients, especially post hip fracture

    Human vaccines & immunotherapeutics

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