Fonsartan
Across all fields, 1 paper: none in people yet, 1 in animals
- 1 lab
- Animals1
Outcomes
4Endothelial function
upin rats1
1 study
Endothelial function
upin rats1
Fonsartan improves endothelial function in rats.
“cardiac function and metabolism as well as endothelial function were significantly improved.”
Animalshypertensiveblood vessel10 mg. kg(-1). d(-1)15 months
Hypertension (Dallas, Tex. : 1979)
Cardiac function
upin rats1
1 study
Cardiac function
upin rats1
Fonsartan improves cardiac function in rats.
“cardiac function and metabolism as well as endothelial function were significantly improved.”
Animalshypertensiveheart10 mg. kg(-1). d(-1)15 months
Hypertension (Dallas, Tex. : 1979)
Left ventricular hypertrophy
downin rats1
1 study
Left ventricular hypertrophy
downin rats1
Fonsartan prevents left ventricular hypertrophy in rats (completely prevented).
“left ventricular hypertrophy was completely prevented in fonsartan-treated animals.”
Animalshypertensiveheart10 mg. kg(-1). d(-1)15 months
Hypertension (Dallas, Tex. : 1979)
Lifespan
upin rats1
1 study
Lifespan
upin rats1
Fonsartan extends lifespan in rats (doubled lifespan to 30 months).
“Fonsartan doubled the lifespan to 30 months in SHR-SP, which was comparable to the lifespan of normotensive Wistar-Kyoto rats.”
Animalshypertensive10 mg. kg(-1). d(-1)lifelongn = 90
Hypertension (Dallas, Tex. : 1979)