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Intervention1 paper

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NatureModel organisms·24 Sep

Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila

mTOR signalling

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Nutrient sensing1
Thor1
mTOR signalling1

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Direct AMPK activation modestly lengthens lifespan in short-lived species

ResearchFight Aging!

Declining chaperone-mediated autophagy prevents macrophages from clearing senescent cells with age

ResearchNature Aging and 1 more

Senescence-inhibiting isoform Δ133p53α slows premature aging in mice

Researchnpj Aging

Trials

Registered6 Oct 2026

AKG and Brain Health in Aging

Phase 2 · University of Oklahoma

Registered2 Oct 2026

Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

Registered7 Oct 2026

AI-Based Conversational Social Support for Older Adults With Heart Failure

Chang Gung University of Science and Technology

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