Digital rectal examination

Studies link digital rectal examination with clinically significant prostate cancer.

Digital rectal examination has been studied in 4 papers since 2025: 1 observational study in people, 3 reviews; 4 in the past year. The newest paper, Oct 27, 2026: “Early Detection of Prostate Cancer: Advances in Screening, Biomarkers, and Imaging Strategies”.

4 papers study it1 findingUpdated Oct 27, 2026

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“Among all DRE-positive patients with PSA < 4 ng/mL, PCa and csPCa detection rates were 67.9% and 35.7%, respectively”

Studies link digital rectal examination with clinically significant prostate cancer.

Clinically significant prostate cancer

upin humans1+36% clinically significant prostate cancer detection rate

1 study

Digital rectal examination predicts clinically significant prostate cancer in humans (DRE-positive patients with PSA < 4 ng/mL) (35.7% clinically significant prostate cancer detection rate).
“Among all DRE-positive patients with PSA < 4 ng/mL, PCa and csPCa detection rates were 67.9% and 35.7%, respectively”
HumansDRE-positive patients with PSA < 4 ng/mLprostatemales
Clinical Relevance of Digital Rectal Examination in Men With Low and Very Low Prostate-Specific Antigen (PSA): Reassessing Its Diagnostic Value in the MRI Era and in Light of Modern Guidelines
CureusDec 13, 2025