Digital breast tomosynthesis plus synthesised two-dimensional mammography

Intervention

1 paper1 finding

  • 1 lab
  • Human trial1

Associations

1

Invasive interval breast cancers

downin humans1OR 0.76

1 study
  1. Digital breast tomosynthesis plus synthesised two-dimensional mammography lowers the risk of invasive interval breast cancers in humans (Adjusted OR 0.76, 95% CI 0.55–1.06; 14.2 versus 18.6 cases per 10 000 screen-negative women).

    Human trialNegative screening result; compared with digital mammographybreast24 monthsfemales

    Invasive interval breast cancer rates after digital breast tomosynthesis plus synthesised mammography versus digital mammography screening (TOSYMA): 24-month follow-up of the multicentre, open-label, randomised, controlled, superiority trial

    The Lancet. Oncology9 Oct 2026

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