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C1C2-CONJUGATED GD-DO3A raft copolymer

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Institute of Neurological Disorders and Stroke
  • Animals1

Outcomes

1

Blood-brain barrier targeting

upin mice1

1 study

  1. C1C2-CONJUGATED GD-DO3A raft copolymer improves blood-brain barrier targeting in mice.

    “Optimized copolymers were synthesized with the claudin-1 targeting peptide, C1C2, to image BBB targeting in aged mice to show imaging utility.”

    Animals

    Optimized gadolinium-DO3A loading in RAFT-polymerized copolymers for superior MR imaging of aging blood-brain barrier

    Sensors & diagnostics

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