Bis-octanoyl (r)-1,3-butanediol

Intervention1 paper2 findings

  • Human trial1

Outcomes

2

Cognitive function

no changein humans1Moderate certainty

1 study

  1. Bis-octanoyl (r)-1,3-butanediol has no effect on cognitive function in humans.

    “There were no statistically significant longitudinal differences between groups in exploratory functional, activity-based or quality of life outcomes in this pilot study.”

    Human trialolder adults25 g daily12 weeks

    RESULTS OF A DOUBLE-BLIND RCT OF THE FUNCTIONAL EFFECT OF KETONE ESTERS IN OLDER ADULTS · GSA 2024 abstract · 31 Dec 2024

Physical function

no changein humans1Moderate certainty

1 study

  1. Bis-octanoyl (r)-1,3-butanediol has no effect on physical function in humans.

    “There were no statistically significant longitudinal differences between groups in exploratory functional, activity-based or quality of life outcomes in this pilot study.”

    Human trialolder adults25 g daily12 weeks

    RESULTS OF A DOUBLE-BLIND RCT OF THE FUNCTIONAL EFFECT OF KETONE ESTERS IN OLDER ADULTS · GSA 2024 abstract · 31 Dec 2024

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