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ANTI-CCL2 antibody

Intervention

1 paper2 findings

  • Animals1

Outcomes

2

Mechanical pain hypersensitivity

downin mice1

1 study

  1. ANTI-CCL2 antibody decreases mechanical pain hypersensitivity in mice.

    “CCL2-neutralising antibody suppressed, whereas recombinant-CCL2 increased pain hypersensitivity in SAMP8.”

    Animalsin SAMP8 mice with palatal mucosal incisiontrigeminal ganglion

    Ageing-Related Macrophage Polarisation in the Trigeminal Ganglion Enhances Incisional Intraoral Pain

    Oral diseasesOct 28, 2024

Macrophage recruitment

downin mouse cells1

1 study

  1. ANTI-CCL2 antibody decreases macrophage recruitment in mouse cells.

    “an effect that was mitigated by preincubation with antibodies to either CCL2 or osteopontin”

    Cellsin vitro senescent FAP mediumskeletal muscle

    Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages

    Aging cellDec 19, 2023

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