AKB-9778
- 1 lab in 1 country
- Funders: Deutsche Forschungsgemeinschaft and 2 more
- 2 of 2 findings with company ties
- Animals1
Outcomes
2Intraocular pressure
downin mice1
1 study
Intraocular pressure
downin mice1
AKB-9778 decreases intraocular pressure in mice.
“AKB9778 improved SC function in aged mice as judged by increasing SC area and lowering of IOP.”
Animalsin aged mice
Inhibition of VE-PTP rejuvenates Schlemm's canal in aged mice and acts via Tie2
PloS oneMay 16, 2025
Schlemm's canal area
upin mice1
1 study
Schlemm's canal area
upin mice1
AKB-9778 increases schlemm's canal area in mice.
“AKB9778 improved SC function in aged mice as judged by increasing SC area and lowering of IOP.”
Animalsin aged mice
Inhibition of VE-PTP rejuvenates Schlemm's canal in aged mice and acts via Tie2
PloS oneMay 16, 2025
Latest
1 in 12 monthsbioRxiv
Reversible hypervascularization drives cognitive decline and blood-brain barrier damage during aging
Preprint: experiments in miceInterventions
PLOS One
Inhibition of VE-PTP rejuvenates Schlemm's canal in aged mice and acts via Tie2
Experiments in miceInterventions