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PSEN1E280ACARRIERSTATUS

There is 1 paper on PSEN1E280ACARRIERSTATUS in aging research: 1 observational study in people.

Gene

1 paper studies it1 finding

See all 1 papers on PSEN1E280ACARRIERSTATUS

At a glance

The findings reach people, from one lab or study. 1 lab in 2 countries.

“Carriers had higher plasma p-tau217 levels than non-carriers.”
Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's diseaseAlzheimer's & dementia : the journal of the Alzheimer's Association2022doi:10.1002/alz.12906
Humans: a single group. Cells, worms or flies and mice: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 2 countries
  • Funders: Alzheimer's Association and others
  • 1 of 1 finding with company ties
  • Humans1

Associations

1

Plasma P-TAU217

upin humans1

1 study

  1. PSEN1E280ACARRIERSTATUS is associated with plasma P-TAU217 in humans (Non-demented presenilin-1 E280A carriers compared with non-carrier family members).

    “Carriers had higher plasma p-tau217 levels than non-carriers.”

    HumansNon-demented presenilin-1 E280A carriers compared with non-carrier family membersplasman = 24

    Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease

    Alzheimer's & dementia : the journal of the Alzheimer's Association

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