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PNMA4

Gene

1 paper2 findings

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Buck Institute for Research on Aging and 8 more
  • Humans1

Effects

1

Reproductive lifespan

is required forin humans1is required forin mice1

1 study

  1. PNMA4 is required for reproductive lifespan in mice.

    “we found that PNMA1 and PNMA4 are necessary for the maintenance of a normal reproductive lifespan.”

    Animals

    The retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity

    Nature aging22 Apr 2025

  2. PNMA4 is required for reproductive lifespan in humans.

    “we found that PNMA1 and PNMA4 are necessary for the maintenance of a normal reproductive lifespan.”

    Humans

    The retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity

    Nature aging22 Apr 2025

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