OSTM1

Gene1 paper1 findingHGNC 21652NCBI Gene 28962Taxon 9606

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.

1 lab in 1 country

Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 4 more

  • Animals1

Effects

1

Cell viability

is required forin mice1

1 study
  1. OSTM1 is required for cell viability in mice.

    Animalsdivergent dependency validated between excitatory and inhibitory neuronsbrain

    Mapping cell-type- and age-dependent neuronal vulnerability through genome-wide in vivo CRISPRi screens in the mouse brain · Neuron · 9 Sep 2026

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