OSTM1
Gene1 paper1 findingHGNC 21652NCBI Gene 28962Taxon 9606
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.
A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.
Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 4 more
- Animals1
Effects
1Cell viability
is required forin mice1
1 study
Cell viability
is required forin mice1
OSTM1 is required for cell viability in mice.
Animalsdivergent dependency validated between excitatory and inhibitory neuronsbrain
Mapping cell-type- and age-dependent neuronal vulnerability through genome-wide in vivo CRISPRi screens in the mouse brain · Neuron · 9 Sep 2026