Nature Aging
Egg-cell protein is needed to keep chromosomes together in mice
Experiments with mice lacking the protein showed that it was required to maintain chromosome connections until egg cells finished maturing.Experiments with mice lacking the protein showed that it was required to maintain chromosome connections until egg cells finished maturing.
Mouse studyMechanisms
Who was studiedFemale mice with Omc1 deletion, against wild-type mouse oocytes
What changedEgg cells lacking OMC1 lost chromosome pairing: ~78% contained separated chromatids in experiments comparing them with wild-type controls
The catchInvestigators knew group assignments during chromosome outcome assessment