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Acta Pharmacologica Sinica·18 Aug

BDKRB2 upregulation by dystrophic microglia drives pain hypersensitivity in aged mice

Experiments in miceMechanisms

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BDKRB21
Microglia inhibition1
S1HLGLU neuron inhibition1

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ER-100 glaucoma trial findings support testing higher dosesTrialsLongevity.Technology and 3 more

New immune cell map reveals how individual immune aging trajectories divergeResearchMedical Xpress and 2 more

Newer cohorts of older Europeans show slower intrinsic capacity lossResearchThe Lancet Healthy Longevity

Trials

AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of Oklahoma Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene Technology AI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

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Mechanisms245 Interventions417 Biomarkers400 Populations530 AI & data162 Industry & policy16

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