Him

1. Him is required for muscle stem cell number in flies.

   “In the flight muscles themselves, Him mutants show an age-dependent decrease in MuSC number, indicating Him is required for MuSC maintenance.”

   Model organismsHim mutation

   The Drosophila Him gene is essential for adult muscle function and muscle stem cell maintenance

   iScience·Jan 10, 2026

2. Him decreases muscle stem cell number in flies.

   “Him mutants have an age-dependent decrease in the number of MuSCs”

   Model organismsin Him mutantsflight muscles

   The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance

   bioRxiv (Cold Spring Harbor Laboratory)·Sep 7, 2024Preprint

More on Muscle stem cell number

1. Him impairs flight ability in flies.

   “there is an age-dependent decline in flight ability.”

   Model organismsin Him mutantsflight muscles

   The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance

   bioRxiv (Cold Spring Harbor Laboratory)·Sep 7, 2024Preprint

1. Him impairs jumping ability in flies.

   “Him mutants have disrupted organisation of the thoracic jump muscle, resulting in reduced jumping ability.”

   Model organismsin Him mutantsthoracic jump muscle

   The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance

   bioRxiv (Cold Spring Harbor Laboratory)·Sep 7, 2024Preprint