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DCTN6

There are 2 papers on DCTN6 in aging research: 1 observational study in people, 1 in animals.

Gene

2 papers study it1 finding

HGNCNCBI GeneTaxon

See all 2 papers on DCTN6

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Alzheimer's Association and 2 more
  • Humans1
  • Animals1

Effects

1

Dystrophic neurites

downin mice1

1 study

  1. DCTN6 prevents dystrophic neurites in aging brains of transgenic mice overexpressing RTN3.

    “DCTN6 deficiency enhanced RTN3 protein levels, high molecular weight RTN3 levels, and hippocampus-specific RIDN formation in aging brains of transgenic mice overexpressing RTN3.”

    Animalsin aging brains of transgenic mice overexpressing RTN3hippocampus

    Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains

    Neurobiology of aging

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