AHA Scientific Sessions 2026 Abstract
Genetic study links two proteins to different cardiovascular risks
Human genetic analyses linked lower activity of one fat-regulating protein to lower risks of four cardiovascular diseases, while a related protein showed little…Human genetic analyses linked lower activity of one fat-regulating protein to lower risks of four cardiovascular diseases, while a related protein showed little association with three.
Mendelian randomizationMechanisms
Who was studiedParticipants in human genetic studies
What changedGenetically predicted ANGPTL4 inhibition was linked to lower cardiovascular risks; ANGPTL3 inhibition had little association with most outcomes
The catchGenetic stand-ins do not measure effects of drugs targeting these proteins