Radiation therapy-induced carotid artery disease

1. Antiplatelet agents are associated with radiation therapy-induced carotid artery disease in humans (HR 2.18, 95% CI 1.41–3.36, p = 0.0004).

   “Baseline use of antiplatelet agents was also associated with the composite event (HR 2.18, 95% CI 1.41–3.36, p = 0.0004)”

   Humanshead and neck cancer treated with radiation therapy9.8 yearsn = 231

   Neck Adiposity Measured on Pre-therapy Oncologic Computed Tomography Scans Predicts the Development of Radiation Therapy-induced Carotid Artery Disease in Patients with Head and Neck Cancer

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

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1. Neck adipose tissue index predicts radiation therapy-induced carotid artery disease in humans (HR 1.04 per unit increase, 95% CI 1.01–1.06, p = 0.0015).

   “neck adipose tissue index was significantly associated with the development of the composite event (HR 1.04 per unit increase, 95% CI 1.01–1.06, p = 0.0015).”

   Humanshead and neck cancer treated with radiation therapyneck9.8 yearsn = 231

   Neck Adiposity Measured on Pre-therapy Oncologic Computed Tomography Scans Predicts the Development of Radiation Therapy-induced Carotid Artery Disease in Patients with Head and Neck Cancer

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

More on Neck adipose tissue index