Progression to late age-related macular degeneration

Disease

2 papers study it4 more mention it4 findings

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  • Humans2

Interventions

1

Fish consumption

no changein humans1HR 0.92

1 study
  1. Fish consumption has no effect on progression to late age-related macular degeneration in humans (HR 0.92, 95% CI 0.78–1.07; P = 0.28).

    “0.92 (0.78-1.07, P = 0.28; AREDS2).”

    HumansAREDS2 participants with no late AMD at baselineeyeFish consumption quartile 4 versus 1n = 3,611

    Adherence to the Mediterranean Diet and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2

    Ophthalmology

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Associations

3

Eye-level candidate risk models

upin humans1

1 study
  1. Eye-level candidate risk models predict progression to late age-related macular degeneration in humans (AUC up to 84.71% ± 4.72%).

    “redefining RPD presence as eye-specific maintained prognostic performance (up to 84.71% ± 4.72%).”

    Humansearly/intermediate AMD1-3 yearsn = 269

    Proposal of a Simpler Eye-Level Risk Model Incorporating Reticular Pseudodrusen for the Clinical Prediction of Late Age-Related Macular Degeneration

    Clinical & experimental ophthalmology

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Fish consumption

downin humans1HR 0.69

1 study
  1. Fish consumption is associated with progression to late age-related macular degeneration in humans (HR 0.69, 95% CI 0.58–0.82).

    “For fish consumption, HRs for late AMD in quartile 4 versus 1 were 0.69 (0.58-0.82, P < 0.0001; AREDS)”

    HumansAREDS participants with no late AMD at baselineeyeFish consumption quartile 4 versus 1n = 4,255

    Adherence to the Mediterranean Diet and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2

    Ophthalmology

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Mediterranean diet

downin humans1HR 0.78

1 study
  1. Mediterranean diet is associated with progression to late age-related macular degeneration in humans (HR 0.78, 95% CI 0.71–0.85).

    “Closer adherence to a Mediterranean-type diet was associated with lower risk of progression to late AMD and to large drusen.”

    HumansNo late AMD at baselineeyeaMedi tertile 3 versus 1Median follow-up of 10.2 years56.5% femalesn = 7,756

    Adherence to the Mediterranean Diet and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2

    Ophthalmology

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