There are 2 papers on pleural mesothelioma in aging research: 2 observational studies in people.
2 papers study it2 more mention it5 findings
See all 4 papers on pleural mesothelioma
“Transferrin and complement C4A were elevated, while beta-2-microglobulin and dermcidin were reduced in pre-diagnostic cases.”
- Humans2
Associations
5Five-marker panel
upin humans1
1 study
Five-marker panel
upin humans1
Five-marker panel predicts pleural mesothelioma in humans (< 1 year before diagnosis in MoMar cohort) (AUC 0.91, p = 0.001).
“with the five-marker panel achieving an AUC of 0.91 (p = 0.001) in MoMar but not reaching significance in EPIC (AUC = 0.88, p = 0.17).”
Humans< 1 year before diagnosis in MoMar cohortplasma
Clinical and experimental medicine
Dermcidin
downin humans1
1 study
Dermcidin
downin humans1
Pleural mesothelioma is associated with dermcidin in humans (pre-diagnostic vs asbestos-exposed controls) (nominal p < 0.05, fold change < 0.75).
“Transferrin and complement C4A were elevated, while beta-2-microglobulin and dermcidin were reduced in pre-diagnostic cases.”
Humanspre-diagnostic vs asbestos-exposed controlsserum
Clinical and experimental medicine
Beta-2 microglobulin
downin humans1
1 study
Beta-2 microglobulin
downin humans1
Pleural mesothelioma is associated with beta-2 microglobulin in humans (pre-diagnostic vs asbestos-exposed controls) (nominal p < 0.05, fold change < 0.75).
“Transferrin and complement C4A were elevated, while beta-2-microglobulin and dermcidin were reduced in pre-diagnostic cases.”
Humanspre-diagnostic vs asbestos-exposed controlsserum
Clinical and experimental medicine
Complement C4a
upin humans1
1 study
Complement C4a
upin humans1
Pleural mesothelioma is associated with complement C4a in humans (pre-diagnostic vs asbestos-exposed controls) (nominal p < 0.05, fold change > 1.3).
“Transferrin and complement C4A were elevated, while beta-2-microglobulin and dermcidin were reduced in pre-diagnostic cases.”
Humanspre-diagnostic vs asbestos-exposed controlsserum
Clinical and experimental medicine
Transferrin
upin humans1
1 study
Transferrin
upin humans1
Pleural mesothelioma is associated with transferrin in humans (pre-diagnostic vs asbestos-exposed controls) (nominal p < 0.05, fold change > 1.3).
“Transferrin and complement C4A were elevated, while beta-2-microglobulin and dermcidin were reduced in pre-diagnostic cases.”
Humanspre-diagnostic vs asbestos-exposed controlsserum
Clinical and experimental medicine
Trial sponsors
Company1 trialPhase 3350 people
Company1 trialPhase 2106 people
Company1 trialPhase 1/2126 people
Company1 trialPhase 1260 people
2 trialsPhase 3269 people
3 trialsPhase 2171 people
2 trialsPhase 215 people
Istituto Oncologico Veneto IRCCS
1 trialPhase 241 people
Funding
2 grants since 2024Vlaamse regering
Vlaamse regeringUniversiteit Gent2024–2025