Nonsyndromic ascending aortic aneurysm
Disease1 paper3 findings
- Humans1
Associations
2Polygenic risk score
upin humans1
1 study
Polygenic risk score
upin humans1
Polygenic risk score predicts nonsyndromic ascending aortic aneurysm in humans (AUC 0.870, 95% CI 0.851-0.889).
Humansfull model including SDOH and PRS
Social Determinants of Health and Polygenic Susceptibility in Nonsyndromic Ascending Aortic Aneurysm · Journal of the American Heart Association · 30 Aug 2026
Polygenic risk score raises the risk of nonsyndromic ascending aortic aneurysm in humans (OR per SD 1.94, 95% CI 1.74-2.16).
Humansafter clinical adjustment
Social Determinants of Health and Polygenic Susceptibility in Nonsyndromic Ascending Aortic Aneurysm · Journal of the American Heart Association · 30 Aug 2026
SDOH composite score
upin humans1OR 1.21
1 study
SDOH composite score
upin humans1OR 1.21
SDOH composite score raises the risk of nonsyndromic ascending aortic aneurysm in humans (OR 1.21, 95% CI 1.04-1.40).
Humansafter clinical adjustment
Social Determinants of Health and Polygenic Susceptibility in Nonsyndromic Ascending Aortic Aneurysm · Journal of the American Heart Association · 30 Aug 2026