Epidermal papillomas

1. CDKN2A increases epidermal papillomas in mice.

   “Continuous p16INK4a expression increases the number of epidermal papillomas formed after carcinogen treatment.”

   Animalsafter carcinogen treatmentepidermis

   Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation

   Nature communications·1 Jun 2020

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