Cardiovascular-kidney-metabolic syndrome stage 4

1. CTI raises the risk of cardiovascular-kidney-metabolic syndrome stage 4 in humans (HR 1.44, 95% CI 1.29–1.60).

   Humanscompared with a persistently low CTI pattern

   Associations of C-ReactiveProtein-Triglyceride-Glucose Index level and its two‑point change with incident Cardiovascular-Kidney-Metabolic Syndrome stage 4: A Nationwide Cohort Study from CHARLS

   Research Square·2 Sep 2026Preprint

More on CTI

1. CuCTI raises the risk of cardiovascular-kidney-metabolic syndrome stage 4 in humans (HR 1.37, 95% CI 1.24–1.51).

   Humansrelative to Q1

   Associations of C-ReactiveProtein-Triglyceride-Glucose Index level and its two‑point change with incident Cardiovascular-Kidney-Metabolic Syndrome stage 4: A Nationwide Cohort Study from CHARLS

   Research Square·2 Sep 2026Preprint

More on CuCTI

1. Adverse pregnancy outcomes raise the risk of cardiovascular-kidney-metabolic syndrome stage 4 in humans.

   Humans11.68 yearsfemalesn = 2,575

   Association between adverse pregnancy outcomes and incidence of advanced cardiovascular-kidney-metabolic disease: a population-based cohort study

   Frontiers in cardiovascular medicine·21 Aug 2026

More on Adverse pregnancy outcomes

1. non-Hispanic Black race is associated with cardiovascular-kidney-metabolic syndrome stage 4 in humans.

   Humansborn between the 1950s and 1990s

   The Prevalence of Cardiovascular-Kidney-Metabolic Syndrome: A Review of Published Estimates and New Findings from BRFSS Surveys

   Cardiovasc medicine (Basel, Switzerland)·3 Feb 2026

1. Male sex is associated with cardiovascular-kidney-metabolic syndrome stage 4 in humans.

   Humansmales

   The Prevalence of Cardiovascular-Kidney-Metabolic Syndrome: A Review of Published Estimates and New Findings from BRFSS Surveys

   Cardiovasc medicine (Basel, Switzerland)·3 Feb 2026