AHA Scientific Sessions 2026 Abstract
About 1 in 347 in US carry heart disease-linked gene variants
An observational analysis estimated 990,722 US carriers of disease-linked variants in the gene for titin, a muscle protein, using population genetic data.An observational analysis estimated 990,722 US carriers of disease-linked variants in the gene for titin, a muscle protein, using population genetic data.
Cross-sectional studyPopulations
Who was studiedPeople represented in public genomic databases
What changedAn estimated 1:347 people in the US carried disease-linked TTN variants
The catchNationwide carrier prevalence was extrapolated from database frequencies rather than directly measured