Alzheimer neuropathologic change

Disease1 paper1 finding

  • Humans1

Associations

1

Plasma eMTBR-tau

upin humans1

1 study
  1. Plasma eMTBR-tau predicts Alzheimer neuropathologic change in humans (AUC=0.91-0.95).

    “neuropathologic classification by plasma eMTBR-tau remained high (AUC=0.91-0.95) even when increasing intervals between blood collection and death up to a decade”

    Humansup to a decade before deathplasmaup to a decade

    Blood eMTBR-tau linked to Alzheimer’s tangles at autopsy · medRxiv · 5 Oct 2026 · Preprint

Plasma eMTBR-tau →

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medRxivHumansPreprint

Blood eMTBR-tau linked to Alzheimer’s tangles at autopsy

Classification accuracy remained high (AUC=0.91–0.95) up to a decade before death, with higher sensitivity and specificity than plasma p-tau217.Classification accuracy remained high (AUC=0.91–0.95) up to a decade before death, with higher sensitivity and specificity than plasma p-tau217.