Aging meniscus injury
1 paper2 findings
- Humans1
Associations
2IRF7
downin humans1
1 study
IRF7
downin humans1
IRF7 predicts aging meniscus injury in humans (AUC > 0.7).
“IRF7 and SPHK1 were significantly downregulated in aging MI and predicted aging MI with high accuracy (area under the curve (AUC) > 0.7).”
Humansin aging meniscus injurymeniscus
Journal of orthopaedic surgery and research19 Dec 2025
SPHK1
downin humans1
1 study
SPHK1
downin humans1
SPHK1 predicts aging meniscus injury in humans (AUC > 0.7).
“IRF7 and SPHK1 were significantly downregulated in aging MI and predicted aging MI with high accuracy (area under the curve (AUC) > 0.7).”
Humansin aging meniscus injurymeniscus
Journal of orthopaedic surgery and research19 Dec 2025
Latest
1 in 12 monthsJournal of Orthopaedic Surgery and Research
Epigenetic silencing of SPHK1-IRF7 axis drives inflammaging in age-related meniscus degeneration via sphingolipid-immune dysregulation
Cohort study in peopleImmune response