Urinary melatonin

Biomarker

1 paper studies it2 more mention it4 findings

See all 3

  • Humans1

Effects

3

Mortality

no changein humans1

1 study
  1. Urinary melatonin has no effect on mortality in humans (p-trend = 0.3).

    “or mortality risk (p-trend = 0.3 in the fully-adjusted model).”

    HumansFully-adjusted modelMean 9.2 yearsmalesn = 2,821

    Association of urinary melatonin levels and aging-related outcomes in older men

    Sleep medicine

Physical function

no changein humans1

1 study
  1. Urinary melatonin has no effect on physical function in humans (p-trends: walking speed 0.4; chair stands 0.7; grip strength 0.6).

    “melatonin levels were not related to physical function scores”

    HumansFully-adjusted modelsmalesn = 2,821

    Association of urinary melatonin levels and aging-related outcomes in older men

    Sleep medicine

Cognitive function change

no changein humans1

1 study
  1. Urinary melatonin has no effect on cognitive function change in humans.

    “there were no associations of urinary melatonin levels with other cognitive test scores, or any cognitive change scores over time.”

    HumansAverage 6.5 yearsmalesn = 2,821

    Association of urinary melatonin levels and aging-related outcomes in older men

    Sleep medicine

Associations

1

Digit Vigilance Test completion time

downin humans1

1 study
  1. Urinary melatonin is associated with digit Vigilance Test completion time in humans (p-trend = 0.01; extreme-quartile means 547.1 versus 561.3 seconds, not significantly different).

    “we observed a significant trend of better Digit Vigilance Test scores (ie, decreased time to completion) at baseline across increasing melatonin quartiles”

    HumansMultivariable-adjusted trend across urinary melatonin quartilesbaselinemalesn = 2,821

    Association of urinary melatonin levels and aging-related outcomes in older men

    Sleep medicine

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