Triglyceride–glucose–muscle loss index

Triglyceride–glucose–muscle loss index improves all-cause mortality risk reclassification in humans (NRI 0.256–0.279; IDI 0.006–0.010).

“improved all-cause reclassification beyond conventional models (NRI 0.256–0.279; IDI 0.006–0.010), whereas cardiovascular reclassification was not significant.”

HumansCKM stages 0–3; beyond conventional modelsn = 5,168

Blood sugar and muscle loss score is linked to earlier death

ESC Congress 2026 abstract·Oct 26, 2026

Triglyceride–glucose–muscle loss index is associated with cardiovascular mortality in humans (HR 2.50 per SD, 95% CI 1.69–3.70).

“TyG-MLI (per SD) was independently associated with higher all-cause mortality (HR 2.24, 95% CI 1.35–3.71) and cardiovascular mortality (HR 2.50, 95% CI 1.69–3.70).”

HumansCKM stages 0–3; NHANES; per SD higher TyG-MLIMedian follow-up 17.5 yearsn = 5,168

Blood sugar and muscle loss score is linked to earlier death

ESC Congress 2026 abstract·Oct 26, 2026

Triglyceride–glucose–muscle loss index is associated with mortality in humans (HR 2.24 per SD, 95% CI 1.35–3.71).

“TyG-MLI (per SD) was independently associated with higher all-cause mortality (HR 2.24, 95% CI 1.35–3.71) and cardiovascular mortality (HR 2.50, 95% CI 1.69–3.70).”

HumansCKM stages 0–3; NHANES; per SD higher TyG-MLIMedian follow-up 17.5 yearsn = 5,168

Blood sugar and muscle loss score is linked to earlier death

ESC Congress 2026 abstract·Oct 26, 2026