Task-related brain activation

1. Bimanual coordination training decreases task-related brain activation in humans.

   “brain activity related to task planning and execution decreased from pretest to posttest in temporo-parieto-frontal areas and subcortical areas in both age groups”

   Human trialPretest-to-posttest comparison in both age groupsTemporo-parieto-frontal and subcortical regions2 weeks

   Relative cortico-subcortical shift in brain activity but preserved training-induced neural modulation in older adults during bimanual motor learning

   Neurobiology of aging·Jun 19, 2017

More on Bimanual coordination training

1. Older age is associated with task-related brain activation in humans.

   “Changes (older > younger) in the inferior prefrontal regions for functional rules and more extensive and bilateral activations for typical and atypical rules.”

   HumansFunctional, typical, and atypical semantic rulesbrainn = 40

   Age-Related Brain Activation Changes during Rule Repetition in Word-Matching

   Frontiers in human neuroscience·Nov 13, 2017

2. Older age is associated with task-related brain activation in humans.

   “the task-related hyperactivation in parietofrontal areas and underactivation in subcortical areas observed in older adults”

   Human trialCompared with younger adultsParietofrontal and subcortical regionsn = 18

   Relative cortico-subcortical shift in brain activity but preserved training-induced neural modulation in older adults during bimanual motor learning

   Neurobiology of aging·Jun 19, 2017

1. atypical semantic rule repetition is associated with task-related brain activation in humans.

   “Greater task-related activation changes for the repetition of the application of atypical rules relative to typical and functional rules”

   HumansRepetition of atypical rules relative to typical and functional rulesbrainn = 40

   Age-Related Brain Activation Changes during Rule Repetition in Word-Matching

   Frontiers in human neuroscience·Nov 13, 2017