Summary secretion score

Biomarker1 paper3 findings

  • Human trial1

Associations

3

Cognitive function

no changein humans1

1 study
  1. Summary secretion score is associated with cognitive function in humans.

    Humansin adults with CKD

    Association between Kidney Tubular Secretory Clearance with Cognitive Function among Adults with CKD in the Systolic Blood Pressure Intervention Trial · Kidney360 · 1 Sep 2026

Dementia

downin humans1HR 0.78

1 study
  1. Summary secretion score lowers the risk of dementia in humans (HR 0.78, 95% CI: 0.63, 0.98).

    Humansin adults with CKDmedian 4.1 years

    Association between Kidney Tubular Secretory Clearance with Cognitive Function among Adults with CKD in the Systolic Blood Pressure Intervention Trial · Kidney360 · 1 Sep 2026

Dementia →

Logical memory delayed score

upin humans1

1 study
  1. Summary secretion score is associated with logical memory delayed score in humans (0.06 higher (95% CI: 0.02, 0.11)).

    Humansin adults with CKD

    Association between Kidney Tubular Secretory Clearance with Cognitive Function among Adults with CKD in the Systolic Blood Pressure Intervention Trial · Kidney360 · 1 Sep 2026

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