Neuro-Oncology
Candidate brain cancer starter cells isolated from older mice
Laboratory experiments found dormant cells in elderly mice’s outer brain layer, and genetically altered cells became capable of forming tumors after a change in growth…Laboratory experiments found dormant cells in elderly mice’s outer brain layer, and genetically altered cells became capable of forming tumors after a change in growth factors.
Animal cell studyMechanisms
Who was studiedCortical cells from elderly mice
What changedIsolated cortical cells lacking p53 became capable of forming tumors after a growth-factor switch
The catchThe tumor-forming result used p53-deficient cells, not unaltered cortical cells