ESC Congress 2026 Abstract
Blood mutations linked to heart, kidney, and metabolic disease
Participants with age-related expansion of mutated blood cells had an adjusted hazard ratio of 1.11 for progression to syndrome stage 4 compared with participants without…Participants with age-related expansion of mutated blood cells had an adjusted hazard ratio of 1.11 for progression to syndrome stage 4 compared with participants without the condition.
Cohort · 433,924 peopleStage 4 cardiovascular-kidney-metabolic syndrome
Who was studied433,924 UK Biobank participants, median 13.6 years, against participants without CHIP
What changedRisk of progression to stage 4 CKM syndrome was higher with CHIP than without (adjusted hazard ratio 1.11)