Proteomic age

Biomarker1 paper2 findings

  • Humans1

Associations

2

Hypoxia

upin humans1

1 study
  1. Hypoxia is associated with proteomic age in humans (B = −0.27 [−0.45, −0.08]).

    “Longitudinally, lower REM oxyhemoglobin saturation (Sathyan: −0.27 [−0.45, −0.08]; Tanaka: −0.17 [−0.31, −0.03]), less slow-wave sleep (Tanaka: −0.03 [−0.05, −0.01])”

    Humanslongitudinally, lower REM oxyhemoglobin saturation, Sathyan clockplasman = 1,554

    Associations between objective sleep measures and proteomic aging: The ARIC Study · GSA 2025 abstract · 31 Dec 2025

Hypoxia →

Sleep apnea syndromes

upin humans1

1 study
  1. Sleep apnea syndromes are associated with proteomic age in humans (B = 0.59 [0.04, 1.14]).

    “Cross-sectionally, SDB (Wang: B = 0.59 [0.04, 1.14]; Sathyan: 0.91 [0.06, 1.76]), less REM sleep (Tanaka: -0.04 [-0.07, -0.01]; Lehallier: -0.03 [-0.06, -0.00] ), and lower sleep efficiency”

    Humanscross-sectionally, Wang clockplasman = 1,554

    Associations between objective sleep measures and proteomic aging: The ARIC Study · GSA 2025 abstract · 31 Dec 2025

Sleep apnea syndromes →

Latest

Nov 2025: 1Dec 2025: 5Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 2Sep 2026: 5Oct 2026: 115
bioRxivHumansPreprint

Blood protein clock tracks shifts in health risks over time

In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher…In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher risk of death.