What does the research say about pathogenic/likely pathogenic variant carriage?

Pathogenic/likely pathogenic variant carriage

There is 1 paper on pathogenic/likely pathogenic variant carriage in aging research: 1 observational study in people.

1 paper studies it1 finding

“Overall, forty-four (8.8%) out of 500 HRI-FHs carried at least one PGV”

Germline testing

upin humans1

1 study

Germline testing is associated with pathogenic/likely pathogenic variant carriage in humans (high-risk individuals due to familial pancreatic cancer) (44/500 (8.8%) carried at least one PGV).
“Overall, forty-four (8.8%) out of 500 HRI-FHs carried at least one PGV”
Humanshigh-risk individuals due to familial pancreatic cancern = 500
Discovering Hereditary Risk Through Surveillance: A Prospective Genetic Analysis of Individuals With Familial Pancreatic Cancer
United European gastroenterology journalFeb 1, 2026

1 paper in 12 months

United European Gastroenterology JournalFeb 15

Cohort study of 500 peoplePancreatic cancer