NLR, MLR, NMLR, and SIRI

1. NLR, MLR, NMLR, and SIRI was not clearly linked with osteoporosis prevalence in humans after multivariable adjustment and FDR correction.

   “NLR, MLR, NMLR, and SIRI were associated with osteoporosis prevalence, but none remained statistically significant after multivariable adjustment and FDR correction.”

   Humansafter multivariable adjustment and FDR correctionn = 16,539

   Association of complete blood cell count-derived inflammatory biomarkers with the prevalence and mortality risk of osteoporosis: evidence from NHANES and an independent Chinese hospital-based case-control cohort

   Frontiers in endocrinology·Oct 30, 2026

More on Osteoporosis prevalence

1. Osteoporosis is associated with NLR, MLR, NMLR, and SIRI in humans (independent Chinese hospital-based case-control cohort; compared with controls).

   “NLR, MLR, NMLR, and SIRI were significantly elevated in osteoporosis patients in both unpaired and matched-pair analyses (all P < 0.05)”

   Humansindependent Chinese hospital-based case-control cohort; compared with controls

   Association of complete blood cell count-derived inflammatory biomarkers with the prevalence and mortality risk of osteoporosis: evidence from NHANES and an independent Chinese hospital-based case-control cohort

   Frontiers in endocrinology·Oct 30, 2026

More on Osteoporosis

1. NLR, MLR, NMLR, and SIRI is associated with mortality in humans (osteoporosis).

   “NLR, MLR, NMLR, and SIRI were positively associated with all-cause mortality (all FDR P ≤0.006)”

   Humansosteoporosis

   Association of complete blood cell count-derived inflammatory biomarkers with the prevalence and mortality risk of osteoporosis: evidence from NHANES and an independent Chinese hospital-based case-control cohort

   Frontiers in endocrinology·Oct 30, 2026