Mean methylation change at 156 photoageing-associated CpG sites

Biomarker

1 paper1 finding

Human trial1

Interventions

Sunscreen

downin humans1

1 study

Sunscreen decreases mean methylation change at 156 photoageing-associated CpG sites in humans.
“The free-living arm demonstrated greater skin darkening and a significantly larger mean change in methylation compared with the SPF-treated arm.”
Human trialcompared with the contralateral arm under normal free-living conditionscreamlower outer-arm skinregular use5 monthsn = 42
DNA marks may help track sun exposure in human skin
Environmental epigenetics6 Aug 2026

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Environmental Epigenetics1 h

DNA marks may help track sun exposure in human skin

In a five-month intervention involving 42 people, sunscreen-treated arms showed smaller changes in DNA marks than the opposite arms under everyday conditions.In a five-month intervention involving 42 people, sunscreen-treated arms showed smaller changes in DNA marks than the opposite arms under everyday conditions.

Non-randomised trial in 42 peopleSkin

Paper

Mean methylation change at 156 photoageing-associated CpG sites

Interventions

Latest

DNA marks may help track sun exposure in human skin

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