Mean intrinsic RR interval

Advanced age increases mean intrinsic RR interval in mice.

“This loss of high-frequency signal processing within intrinsic SAN signatures resulted in a marked increase in the mean intrinsic RR interval.”

Animalsduring double autonomic blockade

Emergence of heartbeat frailty in advanced age I: perspectives from life-long EKG recordings in adult mice

GeroScience·27 Jun 2022