Macromolecular fraction

1. Macromolecular fraction is associated with stage of Parkinson's disease in humans (r = -0.58).

   “and stage of PD in PD patients (r = -0.58 in GM, r = -0.55 in WM-GM, r = -0.52 in WM).”

   Humansin PD patientsgray matter

   MRI-Based Quantitative Assessment of Normal-Appearing White and Gray Matter Demyelination in Multiple Sclerosis, Parkinson's Disease, Long COVID, and Normal Aging

   Biomedicines·28 Jul 2026

1. Macromolecular fraction is associated with Expanded Disability Status Scale in humans (r = -0.71).

   “Significant correlations were found between MPF and EDSS in MS patients (r = -0.71 in GM, r = -0.58 in WM-GM, r = -0.44 in WM)”

   Humansin MS patientsgray matter

   MRI-Based Quantitative Assessment of Normal-Appearing White and Gray Matter Demyelination in Multiple Sclerosis, Parkinson's Disease, Long COVID, and Normal Aging

   Biomedicines·28 Jul 2026

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