2 findings
“higher microstructural integrity at baseline of both the lateral and medial pathways to be associated with better verbal fluency performance at baseline”
Associations
2Phenoconversion to manifest neurodegenerative disease
downin humans1
1 study
Phenoconversion to manifest neurodegenerative disease
downin humans1
Lateral and medial pathway microstructural integrity is associated with phenoconversion to manifest neurodegenerative disease in humans (isolated rapid eye movement sleep behavior disorder) (HR < 0.51, P < 0.05).
“higher integrity of both pathways at baseline was associated with reduced future risk of phenoconversion in iRBD”
Humansisolated rapid eye movement sleep behavior disordernucleus basalis of Meynert white matter pathwaysn = 67
Cholinergic white matter pathways integrity in prodromal and early manifest Lewy body disease
Brain communications
Verbal fluency performance
upin humans1
1 study
Verbal fluency performance
upin humans1
Lateral and medial pathway microstructural integrity is associated with verbal fluency performance in humans (β = 3.29-3.52, P < 0.05).
“higher microstructural integrity at baseline of both the lateral and medial pathways to be associated with better verbal fluency performance at baseline”
Humansnucleus basalis of Meynert white matter pathwaysbaseline
Cholinergic white matter pathways integrity in prodromal and early manifest Lewy body disease
Brain communications