What does the research say about L1 CT attenuation?

L1 CT attenuation

There is 1 paper on L1 CT attenuation in aging research: 1 observational study in people. The newest story, Oct 30, 2026: “Bone scan readings show different age patterns by sex”.

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“L2 reproduced L1 closely (limits of agreement +/-45 HU); ribs did not (+/-68 to +/-82 HU).”

Sex-specific skeletal ageing trajectories and reference centiles across vertebrae and ribs in over 78,000 patientsmedRxiv2026doi:10.64898/2026.10.30.26363202

Humans1

Associations

L2 CT attenuation

no changein humans1

1 study

L2 CT attenuation predicts L1 CT attenuation in humans (Limits of agreement +/-45 HU for L2; +/-68 to +/-82 HU for ribs).
“L2 reproduced L1 closely (limits of agreement +/-45 HU); ribs did not (+/-68 to +/-82 HU).”
Humanslumbar vertebran = 78,620
Bone scan readings show different age patterns by sex
medRxivOct 30, 2026Preprint

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medRxivOct 30

Bone scan readings show different age patterns by sex

Across bone sites, the estimated decrease from age 40 to 80 was a median 34.1% in women versus 12.8% in men.Across bone sites, the estimated decrease from age 40 to 80 was a median 34.1% in women versus 12.8% in men.

Preprint: cross-sectional · 78,620 peopleBiomarkers

Paper

Journal of Clinical DensitometryNov 17

Opportunistic Screening for Low Bone Mineral Density in Routine Computed Tomography Scans: A Brazilian Validation Study

Study in peopleBiomarkers